A Vault Nanoparticle Vaccine Induces Protective Mucosal Immunity
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چکیده
منابع مشابه
A Vault Nanoparticle Vaccine Induces Protective Mucosal Immunity
BACKGROUND Generation of robust cell-mediated immune responses at mucosal surfaces while reducing overall inflammation is a primary goal for vaccination. Here we report the use of a recombinant nanoparticle as a vaccine delivery platform against mucosal infections requiring T cell-mediated immunity for eradication. METHODOLOGY/PRINCIPAL FINDINGS We encapsulated an immunogenic protein, the maj...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0005409